Depends on your vSphere License you maybe aldready have VMware VDP, but i have read that it goes end of life in the near future.
Otherwise
- Veeam B&R
- Nakivo
- HPE (Previously Trilead) VM Explorer (IIRC they sold it again)
- Altaro VM Backup
- Veritas BackupExec
- and countless other like Avamar,Comvault, NetBackup
Regards
Joerg